Andrew Luck went 21-for-38 to for 228 yards with three TD passes and rushed for another score to lead the Indianapolis Colts to a stunning 39-33 win over the previously undefeated Denver Broncos in Peyton Manning's first game at Lucas Oil Stadium since switching Uniform on Sunday.

Luck continued to be sensational for the up-and-coming Colts this season, but this time he come up with a performance that would be cherished by hardcore Colts fans for quite some time.

"It's not real fun watching him," Luck said of Manning via ESPN. "But he is something to watch."

The Stanford product shredded the Colts vaunted pass-rushing defense with accurate passes to his targets and then came through with a 10-yard TD rush to give his team a 33-14 lead in the third quarter.

Despite the turnovers, Manning and the Broncos still had a chance to snatch the game but they simply failed to execute their offense perfectly down the stretch.

Manning went 29-for-49 for 386 yards with three TDs and one interception in his return game in Indianapolis after he was released by the Colts and subsequently joined the Broncos in 2012.

"This is a game we need to learn from. We, I guess, had four turnovers and still somehow had a chance to win that game," Manning told ESPN after the loss. "I would have liked to have seen it go to a two-point game down there toward the end and see what would have happened, but it never quite got to that point.

"You can go back to different parts of the game and we got behind, mistakes there, but we still had a chance there at the end. We certainly have to improve from this game because we weren't as sharp execution-wise as we'd like to be," he added.