The U.S. National Library of Medicine released a review in March 2012 of all available clinical trials involving garlic's effectiveness for the common cold. The intent was to explore clinical evidence for the popular belief that garlic "is good for" colds in humans.

Garlic has been scientifically proven to possess anti-microbial properties

Traditional, anecdotal, and even clinical research supports the fact that the allicin contained in garlic has both anti-bacterial and anti-viral properties. The medical journal Applied Microbiology and Biotechnology published a clinical study in 2001 stating that garlic has "a wide spectrum of actions." Garlic kills bacteria, viruses, protozoa, and fungus. The researchers commented that because of the popularity of natural and herbal treatments for a variety of illnesses and conditions, interest in medicinal plants is now at the forefront of investigation in the field of pharmacology.

Garlic has positive effects on the immune and cardiovascular systems

In addition to its anti-microbial properties, garlic has positive effects on the immune and cardiovascular systems. The Journal of Nutrition published a 2006 critical review which discussed the effectiveness of garlic in the treatment of cardiovascular disease. The medical journal stated that scientists have established that cardiovascular disease is helped by the consumption of garlic on a regular basis. Garlic lowers "bad" cholesterol levels, lowers blood pressure, and provides antioxidants.

Of particular interest is the comment made by the authors in the study regarding mixed reviews in some clinical trials involving garlic. The researchers noted that many of the studies were conducted improperly, affecting outcomes. Conflicting evidence was due to several factors: a variety of garlic preparations were used, there may have been mistakes with subject (patient) selection, the study was not properly randomized, or the duration of the trial was too short.

Garlic "may" help prevent the common cold

Regarding clinical evidence that garlic either prevents or treats the common cold, only one clinical study was performed "correctly," according to the authors gathering evidence for the venerable Cochrane Database for Systematic Reviews. In this study, 146 participants took garlic daily for three months. The study was randomized and placebo controlled. Other controls included no treatment for colds at all, or using other forms of treatment. Participants in the garlic group had fewer colds than those in any of the other groups. The length of the colds were roughly the same in all groups, between four and five days. The conclusion of the clinical trial was that daily consumption of garlic "may" help to prevent colds, but larger studies need to be done to confirm the possibility.

There are no randomized, controlled, and properly conducted medical studies to show if garlic either reduces the severity or length of a cold when a person begins to take garlic at the beginning of a cold.

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