HIV Cure: Likely "Temporary" According to a Leading Scientist; Biggest Problem Is Monitoring Virus' Return
Timothy Ray Brown's HIV "cured" status lead to more talks regarding an effective cure against the virus. However, a leading scientist say that HIV cure can look differently as it may only be "temporary" eradication of the virus.
Temporary Cure
Several research projects are ongoing to create the very first effective cure against the deadly AIDS-causing virus - HIV. The Berlin patient named Timothy Ray Brown made experts curious on how to use the genetic mutation factor CCR5 delta as functional treatment against HIV but a leading scientist points that the cure may only be a "temporary" process on eradicating the pathogen.
Robert Siliciano is a professor of molecular biology and genetics at Johns Hopkins University and one of the world's lead researchers on HIV. He stressed a surprising prediction on how the HIV cure will truly function if ever made as early as today.
"What a 'cure' means for the masses at least in the near future, might look very different. It might actually be but a temporary eradication of the virus," according to Seattle Weekly.
Siliciano has his own laboratory and runs it with his wife Janet, working on a strategy called "kick and kill" that would activate and destroy latent HIV in the body. Early results of the kick-and-kill strategy was not as impressive as it can only reduce the virus but unable to completely remove it out of the body.
Major Problem When Dealing HIV
HIV possesses amazing biological traits such as constant genetic mutation preventing antibodies from catching up like rhinovirus, 'cloaking' shield to avoid detection and capacity to become dormant for an indefinite period of time inside host cells.
One of the biggest problems regarding HIV and the creation of an effective cure is that scientists are unable to monitor its activity accurately. Medical experts won't exactly know when HIV will return after any treatment which may cause transmission without notice via sexual intercourse or through pregnancy.
Few cases of 'cure' from HIV have been reported and science somehow managed to explain on what took place. But every case has been different which science aims to determine in order to answer such questions.
1. After HIV levels are reduced, when will it strike back?
2. Is the quantity of antiretroviral therapy enough to prevent transmission sexually?
3. Does the status "cured" allow sexual interactions?
4. Will that status secure the future of my child if I am pregnant?
5. Will my CD4 levels become normal after the painful and uncomfortable treatment?
Siliciano may simply be pointing on the better understanding of the virus' activity in relation with the latest drugs, biological interactions and any other factors which could be helpful on the discovery of an effective cure.