Kaley Cuoco is the center of Twitter attention Wednesday night during People's Choice Awards 2013. The actress was in high spirits ahead of the event, telling followers the night is "gonna be awesome."

Kaley Cuoco is the center of Twitter attention Wednesday night during People’s Choice Awards 2013. The actress was in high spirits ahead of the event, telling followers the night is “gonna be awesome.” (Image: Twitter)

Cuoco, who plays Penny in the CBS hit sitcom "The Big Bang Theory," lost to Glee's Lea Michele for "Favorite Comedic TV Actress." But fans showered her with love on Twitter, anyway.

Meanwhile, Jennifer Aniston won the film counterpart of Michele's award. The soon-to-be-wed former Friends sweetheart won "Favorite Comedic Movie Actress."

"I can't thank you enough for allowing me to be honored with this again and after supporting me for almost 20 years and allowing me to keep doing this," Aniston said in her speech.

The Big Bang Theory's Wolowitz and Koothrappali Tweet for Penny

Cuoco's "The Big Bang Theory" co-star Simon Helberg (‏@simonhelberg) tweets: "Heading to the People's Choice Awards hosted by the lovely @KaleyCuoco. Finally, an award show for people. Tonight on CBS!"

Cuoco, who seems to be good friends with the actors playing Howard Wolowitz and Rajesh Koothrappali, get shout outs from the two for her PCA hosting.

Kunal Nayyar (‏@kunalnayyar) tweets, "Tune in tonight to watch my bestie @KaleyCuoco host @peopleschoice award!!!! Fingers crossed that @BigBang_CBS WINS!!!!"

Kaley Cuoco: Twitter showers love on night of People's Choice Awards

If I had known Kaley Cuoco was hosting, I would've watched it from the beginning. - Sondra Pearson ‏@Sh_tSondraSays

Okay, I like Glee but @kaleycuoco and Jim Parsons got robbed - Sean Sinclair ‏@leafsandbeer

Jim Parsons was robbed. As for Comedic Actress, I was torn between Kaley Cuoco and Zooey Deschanel (sadly, neither won). - Ashley Crockett ‏@ACroquet

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