Awards will be granted to original discoveries that lead to understanding of the human body or treatment of diseases, says committee secretary.

For unraveling some of the enigma tied to obesity, two scientists may share the highly-desired prize worth $1.5 million.

On the other hand, a Japanese professor, who discovered that stem cells can be made from ordinary skin cells, is also a top candidate for the award.

Douglas Coleman from Canada and American Jeffrey Friedman have already won a number of prizes for their discovery of Leptin, a hormone that controls food intake and body weight.

Japanese Shinya Yamanaka has come up with a breakthrough that led to significant progress in stem cell research reducing the need for using human embryos.

Coleman and Freidman have already received the Lasker Award, a forerunner to the Nobel for proving that obesity is often associated with metabolic distractions or the lack of the Leptin hormone, instead of being a self-induced problem, according to reports from the Associated Press.

Yamanaka won the Lasker Award in 2009 and shared Israel's Wolf prize this year.

Previous Nobel winners have won numerous accolades and honors before being considered for the Nobel Prize.

The Nobel Prizes are commonly regarded as the most esteemed awards given for intellectual accomplishments all over the globe.

The categories include medicine, physics, chemistry, literature and peace.

The prizes are given out on Dec. 10 of each year during the commemoration of Nobel's death in 1896.

It is a possibility that Yamanaka of Kyoto University in Japan and the Gladstone Institute of Cardiovascular Disease in San Francisco could share the prize with British cloning pioneer John Gurdon or Canadian stem cell researcher James Till.

Till discovered blood stem sells that have saved the lives of thousands of leukemia patients.

There are so many Nobel-worthy achievements in medicine which makes it hard to choose a winner.