Small Dose Testosterone Delays Muscle Aging, Research Reveals
For the Aussie patients who are interested in anti-aging treatment, a new Australian study has good news.
A small dose of the male hormone testosterone taken by healthy postmenstrual women will likely delay muscle aging and combat chronic heart disease according to a new Australian research by Dr Vita Birzniece and Professor Ken Ho of Sydney's Garvan's Institute of Medical Research.
It was found out through the research that a 40mg/day of the pure crystalline testosterone when taken orally is just the right amount of dose the human body. With this minimal amount, there will be no spill over to the bloodstream and other organs. Hence, there will be no harmful side effects of testosterone as compared when taken in hefty dose through injection, gel or patch through the skin. Bad side effects of testosterone include aggressive behaviours, heightened libido and growing of facial hair and having deeper voice for women.
"The novel aspect of this research is that only the liver gets tickled with testosterone. It is a new way of using an old hormone. This is a great advantage because it avoids the unpleasant behavioural effects of high doses of testosterone injected into the bloodstream and mascunilising effects in women," said Mr Ho.
"We saw that low dose testosterone, taken orally, had the same magnitude of effect on whole body protein metabolism as when it is injected in larger doses in men," as explained further by Ms Birzniece.
"This is really, hopeful, because if we can see the same effect on protein metabolism at this stage, we believe it will translate into the same increase in muscle mass that we see from testosterone delivered systematically, yet avoiding all the unpleasant side effects," said Ms Birzniece.
Ms Birzniece and Mr Ho will conduct another research on healthy men with lower testosterone levels and how they can take advantage of the hormone. If they will see the same promising effect to men, then their next step is to announce that indeed, small dose testosterone is a safer treatment for muscle aging.
"If we can reduce muscle wasting in frail elderly people, this would prevent many falls, and therefore osteoporotic fractures," said Mr Ho.