Musician Pharrell Williams
Musician Pharrell Williams attends "The Night That Changed America: A Grammy Salute To The Beatles" in Los Angeles, California in this file photo taken January 27, 2014. Williams, the R&B singer of the hit song "Happy" and a music producer, will join NBC's singing contest "The Voice" as a coach for its seventh season in the fall, the network said on Monday. REUTERS/Jonathan Alcorn/Files REUTERS/Jonathan Alcorn/Files

Perhaps motorists could now equate the famous reminder "Don't drink and drive" to "Don't take selfies and drive." A woman from North Carolina died in a head-on collision on a US highway, ironically just seconds after posting a selfie and 'happy' status on Facebook.

"The happy song makes me HAPPY!" Courtney Sanford posted on her Facebook timeline at 8.33am on Thursday.

Pharrell Williams is the singer of 'Happy.' The feel good song, posted on YouTube in November 2013, has become a worldwide phenomenon.

At 8.34am, the 32-year old was gone with the wind after a fatal crash accident. She crashed head-on into a recycling truck while crossing a median road. The impact was strong and major because Ms Sanford's car immediately burst into flames, while the truck was forced off the road and hit a tree. The truck driver was unhurt.

Police said she was on her way to work along Interstate 85 in North Carolina at the time of the accident. They found no evidence that drink, drugs or speed were factors in the collision.

It was Ms Sanford's friends who linked the car accident, saying a number of her posts online that day appeared to happen at the same time of the incident itself.

"The crash was a real-life public service advert showing what happens when you text and drive," Lt Chris Weisner, High Point Police Department spokesperson, was quoted by The Independent.

"In a matter of seconds, a life was over just so she could notify some friends that she was happy. It's really not worth it," he said. "As sad as it is, it is also a grim reminder for everyone... you just have to pay attention while you are in the car."

Ms Sanford was the lone occupant when the fatal crash accident happened.

Ms Sanford seemed to have a fetish uploading pics and statuses on social media while behind the wheel, as police found evidence on her mobile phone.